The nurse is assessing a patient in a family practice clinic. The patient had extensive testing to rule out Hodgkin disease. Which of the following characteristics would indicate Hodgkin disease?

A. Excessive thirst and hunger are characteristic of diabetes mellitus, not Hodgkin disease. B. The Philadelphia chromosome is associated with chronic myeloid leukemia, not Hodgkin disease. C. Reed-Sternberg cells are the diagnostic hallmark of Hodgkin disease and their presence confirms the disease. D. Cyanosis is a general sign of hypoxia and is not specific to Hodgkin disease.