The nurse is assisting in the care of a client in an inpatient mental health facility. Select the 4 manifestations of withdrawal for which the client is at risk.

A. Diaphoresis: Common during opioid and stimulant withdrawal due to autonomic hyperactivity. B. Hypothermia: Withdrawal typically causes hyperthermia or temperature instability, not hypothermia. C. Hyperreflexia: Seen in stimulant withdrawal as part of CNS overactivity. D. Anxiety: A hallmark of both opioid and stimulant withdrawal, contributing to restlessness and agitation. E. Slurred speech: More characteristic of intoxication with CNS depressants (e.g., alcohol, benzodiazepines), not withdrawal from opioids or stimulants. F. Insomnia: Withdrawal from opioids and stimulants often disrupts sleep patterns, causing difficulty falling or staying asleep.