The nurse is caring for a client who has heart failure and a history of asthma. The nurse reviews the provider's orders and recognizes that clarification is needed for which of the following medications?

Rationale: A. Isosorbide dinitrate is a nitrate used to reduce preload and manage heart failure symptoms; it is safe for clients with asthma. B. Fluticasone is an inhaled corticosteroid used to manage asthma and does not worsen heart failure. C. Captopril is an ACE inhibitor that treats heart failure and is safe for clients with asthma. D. Carvedilol is a non-selective beta-blocker. Non-selective beta-blockers can exacerbate asthma by causing bronchoconstriction. In clients with asthma, beta-blocker therapy should be clarified, and cardioselective options are generally preferred.