The nurse is caring for a client who has symptoms consistent with a primary (first) Herpes Simplex Virus (HSV) outbreak. Which of the following symptoms is most consistent with this diagnosis?

Rationale: A. Amnorrhea (amenorrhea) is absence of menstruation and is not a feature of primary HSV infection. B. Flu-like symptoms (fever, malaise, myalgia, headache, and regional lymphadenopathy) are common with a primary herpes simplex outbreak and often accompany the initial lesions. C. Abdominal cramping is not a characteristic symptom of primary HSV infection. D. Bleeding between menstrual periods is unrelated to herpes simplex and suggests a gynecologic or hormonal issue rather than primary HSV.