The nurse is caring for a client with a double lumen peripherally inserted central catheter (PICC) line on the right upper extremity. that flushes easily but does not have a blood return. Normal saline is infusing through one port and a vasopressor agent is infusing through the other port. Which intervention(s) should the nurse implement? Select all that apply.

A. Stop the infusions and insert an antecubital IV catheter: Stopping both infusions immediately is unnecessary if the PICC line is still flushing easily without resistance or signs of infiltration. B. Aspirate and flush the line until a blood return is obtained: Forcefully aspirating or flushing repeatedly could damage the catheter or cause dislodgement; persistent attempts are not recommended if the line otherwise functions properly. C. Observe the extremity for signs of infiltration: Since there is no blood return, it is critical to monitor closely for swelling, redness, coolness, or pain, which could indicate infiltration or extravasation, especially with a vasopressor. D. Acquire consent for a new PICC line insertion: A new line is not needed immediately if the current PICC remains patent for infusion and there are no signs of complications; invasive procedures should be avoided unless absolutely necessary. E. Continue infusions as long as catheter flushes easily: If the catheter flushes without resistance and no infiltration is observed, infusions can continue, but with increased monitoring to detect any early signs of complications.