The nurse is caring for a newborn with a cleft palate. What finding in the maternal medical record is considered to be contributing factors?
Explanation & Rationale
Choice A reason: While alcohol use during pregnancy is associated with fetal alcohol spectrum disorders, it is not a primary contributor to cleft palate formation. Moderate alcohol use prior to pregnancy does not have a strong causal link to orofacial malformations unless continued into early gestation. Choice B reason: Marijuana use during pregnancy has been associated with low birth weight and neurodevelopmental concerns, but its role in causing cleft palate is not well established. It is not considered a major teratogenic factor for craniofacial anomalies. Choice C reason: Maternal age less than 18 years may be associated with increased risk of poor prenatal care and nutritional deficiencies, but it is not a direct teratogenic factor for cleft palate. Age alone is not a recognized cause of this congenital defect. Choice D reason: Anticonvulsant therapy, particularly with medications such as phenytoin, valproic acid, and carbamazepine, is a well-documented teratogenic risk factor for cleft palate and other craniofacial anomalies. These drugs interfere with fetal development during the first trimester, when the palate is forming, making this the most scientifically supported contributing factor.