The nurse is caring for a patient experiencing a stroke understands the importance of establishing the onset of the stroke before administering a tissue plasminogen activator based on which recommendation

A. The activator is recommended for transient ischemic attacks: Tissue plasminogen activator (tPA) is not indicated for TIAs because symptoms resolve without permanent infarction, and the risks of bleeding outweigh potential benefits. B. The activator is not recommended if the stroke is greater than 3 hours: tPA must be administered within a narrow therapeutic window (generally within 3–4.5 hours from symptom onset) because the risk of intracranial hemorrhage increases significantly after this time. C. The activator is recommended for patients with increased ICP: Increased intracranial pressure is a contraindication to tPA due to the high risk of cerebral bleeding and worsening neurologic injury. D. The activator is not recommended if the stroke is less than 3 hours: This is incorrect, as tPA is most effective and safest when given as early as possible within the approved time window.