The nurse is caring for Jane Doe, an 18-year-old female who is currently admitted on the psychiatric unit. For the past 6 months, Jane reports feeling excessively worried at school and at home. She reports having more frequent headaches, difficulty sleeping, and frequently feeling fatigued. She presents with an anxious affect, wringing her hands, and is avoiding eye contact. Vital Signs: Within expected limits Labs: TSH level, CBC, CMP all within acceptable ranges. Toxicology negative. Alcohol negative.

Choice A reason: Alprazolam is a benzodiazepine used for acute anxiety relief. However, due to its high potential for dependence and sedation, it is not the first-line treatment for generalized anxiety disorder (GAD), especially in young adults. Choice B reason: Sertraline is an SSRI and a first-line treatment for GAD. It is effective for long-term management of anxiety symptoms and has a favorable safety profile. It addresses both somatic and cognitive symptoms of anxiety. Choice C reason: Phenelzine is an MAOI, typically reserved for treatment-resistant depression or anxiety due to dietary restrictions and potential for serious interactions. It is not a first-line agent for GAD. Choice D reason: Clozapine is an atypical antipsychotic used for treatment-resistant schizophrenia. It is not indicated for anxiety disorders and carries significant risks such as agranulocytosis.