The nurse is discussing insulin administration with an assigned patient. The patient reports that she prefers to use only certain sites for insulin injections. The patient questions why rotation of the sites is important. What response by the nurse is most appropriate?

A. "Unsightly fatty tumors can develop when you do not adequately rotate injection sites.": While lipohypertrophy (fatty lumps under the skin) can develop from repeated use of the same injection site, the main reason for rotating sites is to avoid this and lipodystrophy. B. "Rotating your injection sites will help to reduce your risk of infection.": Rotating injection sites can help prevent lipodystrophy, but it does not directly reduce the risk of infection. Proper technique is more important for preventing infection. C. "Failing to rotate injection sites will improve your ability to prevent an insulin reaction.": Failing to rotate injection sites does not prevent insulin reactions. In fact, using the same site too often can cause insulin absorption problems and potentially affect blood glucose control. D. "Rotating your injection sites will help to reduce your risk for lipodystrophy.": Lipodystrophy (which includes lipohypertrophy and lipoatrophy) can occur when insulin is repeatedly injected into the same site. Rotating injection sites helps to reduce the risk of these issues and ensures consistent insulin absorption.