The nurse is discussing treatment for a superinfection with a client and family members. The family asks the nurse what a superinfection is. What is the best response by the nurse?

A. A drug-resistant infection: This is not specific to superinfections. B. An infection caused by a weakened immune system: While a weakened immune system can increase susceptibility to infections, it doesn't directly define a superinfection. C. An infection that is difficult to treat: Difficulty in treatment can occur with various infections, not just superinfections. D. A secondary infection that occurs when microorganisms normally present in the body are killed by the drug used to treat another infection: This accurately describes a superinfection. When antibiotics are used, they might eliminate some beneficial bacteria along with the target infection. This can allow other organisms to overgrow, causing a new infection (superinfection).