The nurse is instructing the parents of a child with sickle cell anemia on safety precautions. What should the nurse emphasize during this teaching?

A. Children with sickle cell anemia should receive all recommended immunizations to protect against infections, which can trigger a sickle cell crisis. B. Participating in sports should be done with caution, and activities that lead to dehydration or overexertion should be avoided. C. Over-the-counter medications should be used cautiously and under the guidance of a healthcare provider, as some medications may not be suitable for children with sickle cell anemia. D. Ensuring adequate hydration is crucial for preventing sickle cell crises. Dehydration can increase blood viscosity, leading to sickling of the red blood cells and subsequent pain and complications.