The nurse is performing intake interviews at a psychiatric clinic. A client with a known history of drug abuse reports having had a heart attack four years ago. Use of which substance places the client at highest risk for myocardial infarction?

A. While excessive alcohol consumption can contribute to cardiovascular issues, including heart attacks, methamphetamine abuse is associated with a higher risk of myocardial infarction due to its potent sympathomimetic effects on the cardiovascular system. B. Benzodiazepines primarily affect the central nervous system and are not typically associated with an increased risk of myocardial infarction. C. Methamphetamine use is known to cause significant cardiovascular effects, including increased heart rate, blood pressure, and vasoconstriction, which can lead to myocardial infarction. D. While marijuana use can have cardiovascular effects, it is generally less potent in its cardiovascular effects compared to methamphetamine.