The nurse is preparing to administer alendronate to a client with osteoporosis. Which laboratory value indicates that the nurse should withhold the medication and contact the healthcare provider? Reference Range: Total Calcium 19 to 10.5 mg/dL (2.3 to 2.6 mmol/L)] Sodium [136 to 145 mEq/L (136 to 145 mmol/L)] Potassium [3.5 to 5 mEq/L (3.5 to 5 mmol/L)] Magnesium [1.3 to 2.1 mEq/L (0.65 to 1.05 mmol/L)]
Explanation & Rationale
A. Magnesium 2.4 mEq/L (2.4 mmol/L): This value is slightly above the reference range, but mild hypermagnesemia is not a direct contraindication for alendronate administration. It does not require immediate withholding of the drug. B. Sodium 132 mEq/L (132 mmol/L): This reflects mild hyponatremia, which is unrelated to alendronate’s main risks and would not usually warrant withholding the medication unless symptomatic. C. Calcium 13.0 mg/dL (3.3 mmol/L): Alendronate is a bisphosphonate used to treat osteoporosis by inhibiting bone resorption, which in turn lowers serum calcium levels. Administering alendronate to a client who is already hypercalcemic could worsen the condition. D. Potassium 5.2 mEq/L (5.2 mmol/L): This is a mild elevation in potassium and is not directly linked to alendronate’s safety profile, so it would not require withholding the dose.