The nurse is preparing to administer ciprofloxacin (Cipro) to a client. Which of the following administration guidelines should the nurse provide to the client? (Select all that apply)

A. Take ciprofloxacin on an empty stomach for best absorption: Ciprofloxacin is best absorbed when taken at least 1 hour before or 2 hours after meals. Food, especially calcium-rich foods, can reduce its bioavailability. Administering on an empty stomach maximizes therapeutic effectiveness. B. Avoid prolonged sun exposure while taking ciprofloxacin: Ciprofloxacin can cause photosensitivity, increasing the risk of sunburn or skin reactions. Patients should use protective clothing and sunscreen. This precaution helps prevent painful or harmful dermatologic effects. C. Take ciprofloxacin with a full glass of water: Taking the medication with a full glass of water promotes proper dissolution and reduces the risk of esophageal irritation or ulceration. Adequate fluid also supports renal excretion, which is important for drug clearance. D. Avoid taking ciprofloxacin with dairy products: Calcium in dairy binds to ciprofloxacin, forming insoluble complexes that reduce absorption. Patients should separate dosing from dairy or calcium-containing products to maintain therapeutic drug levels. E. Ensure adequate fluid intake while taking ciprofloxacin: Sufficient hydration helps prevent crystalluria and kidney injury, which are potential adverse effects of ciprofloxacin. Maintaining fluid intake supports renal function and safe drug elimination.