The nurse is providing care to a patient with a 10% TBSA burn injury. Which of the following is a priority intervention for preventing infection?

A. Administer IV antibiotics: IV antibiotics are not routinely indicated for a clean, partial-thickness burn unless there is evidence of systemic infection. Overuse can promote antibiotic resistance and does not prevent initial colonization of the burn wound. B. Clean the burn with mild soap and water: Proper cleansing of the burn removes dirt, debris, and surface bacteria, which is the most effective first-line measure to prevent local infection. Gentle cleaning preserves the integrity of viable tissue while reducing microbial load, lowering the risk of cellulitis or sepsis. C. Keep the burn site open to air: Exposing a burn to air can increase the risk of contamination and infection. Burns require a protective barrier, such as a sterile dressing or topical antimicrobial, to maintain moisture and prevent microbial colonization. D. Apply ice to the burn: Applying ice can cause further tissue damage due to cold injury and vasoconstriction, impairing perfusion and delaying healing. Immediate cooling with lukewarm water is preferred for burn management, not ice.