The nurse is providing discharge instructions to a patient who is prescribed sulfasalazine for the treatment of ulcerative colitis (UC). Which patient statement requires further intervention by the nurse?

A. "I will take my medication on an empty stomach.": Sulfasalazine should be taken with food or after meals to minimize gastrointestinal irritation such as nausea, vomiting, and abdominal discomfort. Taking it on an empty stomach can worsen these side effects and reduce medication tolerance, indicating a need for further teaching. B. "I will call my provider if I get a sore throat.": A sore throat may indicate bone marrow suppression, a serious adverse effect of sulfasalazine that can lead to agranulocytosis or infection. Prompt reporting allows early detection and management, making this an appropriate and important statement. C. "I will drink at least eight glasses of water a day.": Adequate hydration helps prevent crystalluria and kidney complications associated with sulfasalazine. Encouraging increased fluid intake supports renal clearance of the medication and reduces the risk of adverse urinary effects. D. "I will wear a hat and use sunscreen when gardening.": Sulfasalazine can cause photosensitivity, increasing the risk of sunburn. Protective measures such as sunscreen and protective clothing are appropriate to prevent skin damage during sun exposure.