The nurse is providing discharge teaching to a client recovering from a kidney transplant. Which client statement indicates understanding?

A. I will take my antirejection medications for life: Immunosuppressive therapy is required indefinitely after kidney transplantation to prevent activation of the recipient’s immune system against donor antigens. T-cell–mediated and antibody-mediated rejection can occur at any time if immunosuppression is reduced or stopped, making lifelong adherence essential for graft survival. B. I can stop my medications when my glomerular filtration rate returns to normal: A normal or improved GFR reflects adequate graft function but does not indicate immune tolerance. The alloimmune response persists indefinitely, and discontinuation of immunosuppressants can precipitate acute rejection, leading to rapid decline in renal function and possible graft loss. C. If my urine output decreases, I will drink more fluids: Decreased urine output after transplant may indicate acute rejection, renal artery thrombosis, obstruction, or acute tubular necrosis rather than simple dehydration. Increasing fluid intake without evaluation can worsen complications such as fluid overload and delay urgent medical assessment. D. I will drink 8 ounces of water with my medications: While adequate hydration is generally beneficial, a fixed fluid amount with medications is not the critical teaching point. Post-transplant fluid intake is individualized based on renal function, and medication adherence and infection/rejection monitoring take higher priority.