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    Hesi rn 315 pharmacology proctored exam

    The nurse is providing instructions about a client's new medications. How should the nurse explain the purpose of probenecid, a uricosuric drug?

    Explanation & Rationale

    A. Promotes excretion of uric acid in the urine: Probenecid works by inhibiting the reabsorption of uric acid in the renal tubules, leading to increased urinary excretion of uric acid. This action helps lower serum uric acid levels, making it effective in the management of chronic gout and hyperuricemia. B. Prevents the formation of kidney stones: Although lowering uric acid levels can indirectly reduce the risk of uric acid kidney stones, probenecid's primary mechanism is to promote uric acid excretion rather than directly preventing stone formation. Additional measures like hydration are typically emphasized for stone prevention. C. Decreases pain and burning during urination: Pain and burning during urination are usually related to infections or inflammatory processes, not elevated uric acid. Probenecid does not have antimicrobial or analgesic effects and is not used to treat dysuria symptoms. D. Increases the strength of the urine stream: Weak urine flow is commonly associated with bladder outlet obstruction or prostate issues. Probenecid does not act on the urinary tract muscles or prostate and has no role in improving the strength or flow of urination.

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