The nurse is taking care of an adolescent with osteosarcoma. The parents ask the nurse about treatment. The nurse should make which accurate response about treatment for osteosarcoma?

A. Bone marrow transplantation offers the best chance of long-term survival is incorrect. Bone marrow transplantation is not the primary treatment for osteosarcoma. Treatment typically focuses on surgery and chemotherapy. B. Treatment usually consists of surgery and chemotherapy is correct. The main treatment for osteosarcoma involves a combination of surgery (to remove the tumor) and chemotherapy (to treat any potential metastasis). This approach is the standard for achieving long-term survival in most cases. C. Intensive irradiation is the primary treatment is incorrect. While radiation therapy can sometimes be used, it is not the primary treatment for osteosarcoma. Surgery and chemotherapy are the main modalities. D. Amputation of the affected extremity is rarely necessary is incorrect. While limb-sparing surgery is often possible, amputation may still be required in some cases, depending on the location and extent of the tumor. Thus, saying amputation is rarely necessary may be misleading.