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    Hesi bsn 315 rn pharmacology 35504 proctored exam

    The nurse is teaching a client with type 1 diabetes mellitus about the onset, peak, and duration of a new prescription for glargine insulin. If the insulin is self administered at 0800, when is the client most likely to experience hypoglycemia?

    Explanation & Rationale

    A. No peak occurs: Glargine insulin is a long-acting insulin that provides a steady, basal level of insulin without a pronounced peak. Because of its stable release, the risk of hypoglycemia related to peak action is lower compared to other insulins that have distinct peaks. B. Shortly after midnight: This time frame might correspond to the peak of intermediate-acting insulins like NPH, but it is not typical for glargine, which maintains a consistent effect over 24 hours. C. Midmorning: Rapid-acting or short-acting insulins given in the morning may peak midmorning, but glargine’s flat action profile does not cause such peaks or corresponding hypoglycemia during this time. D. Midafternoon: Similar to midmorning, midafternoon hypoglycemia is associated with insulins that have specific peaks, which glargine lacks due to its steady absorption and action profile.

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