The nurse plans care for a client with blood type A positive who requires an emergency blood transfusion. Which blood types should the nurse anticipate administering? Select all that apply.

Rationale: A. AB Rh-positive blood is not compatible with a client who has type A blood. AB blood contains both A and B antigens. Because the client’s plasma contains anti-B antibodies, transfusing AB blood would cause those antibodies to attack the B antigens on the donor red blood cells, potentially leading to a life-threatening hemolytic transfusion reaction. Therefore, AB Rh-positive is unsafe. B. A Rh-positive blood is fully compatible with the client’s blood type. It contains only the A antigen, which matches the client’s blood type, and it is Rh-positive, which aligns with the client’s Rh factor. This makes it the preferred choice for transfusion, ensuring both ABO and Rh compatibility while minimizing the risk of transfusion reactions. C. A Rh-negative blood is also safe for the client. While it lacks the Rh antigen, it still contains the correct A antigen, making it compatible. Rh-negative blood can safely be given to a Rh-positive recipient and is often used in emergency situations if Rh-positive type-specific blood is not available. D. O Rh-positive blood is generally compatible for many recipients with ABO compatibility, but in emergencies, Rh-negative is safer for a type A positive client if the type-specific blood is unavailable. It is not the preferred emergency option when exact matching types like A Rh-positive or A Rh-negative are available. E. O Rh-negative blood is considered a universal donor type for red blood cells. It contains no A or B antigens and is Rh-negative, allowing it to be transfused safely to virtually any ABO and Rh blood type. It is particularly useful in emergency situations when the client’s exact blood type is unknown or when rapid transfusion is required.