The nurse practitioner is educating a 52-year-old man who was recently diagnosed with peptic ulcer disease. Which of the following statements by the patient indicates a need for further teaching?

Choice A reason: This statement is correct because PPIs are most effective when taken once daily, ideally 30 to 60 minutes before the first meal of the day. This timing maximizes acid suppression and helps promote ulcer healing. Choice B reason: This statement is also correct because H. pylori infection is a common underlying cause of peptic ulcer disease, and antibiotics are prescribed to eradicate this bacterium, addressing the root cause. Choice C reason: This statement indicates a need for further teaching. NSAIDs can impair gastric mucosal defenses and increase acid production, which can exacerbate ulcer formation or prevent healing. Patients with peptic ulcers should avoid NSAIDs unless specifically approved by their healthcare provider and often need alternative pain management. Choice D reason: This statement is correct because lifestyle modifications, such as avoiding alcohol, smoking, and certain medications, help prevent recurrence of ulcers and support overall gastrointestinal health.