The nurse preparing isoniazid and rifampin to be administered to a patient knows that these antibiotics are being give for the treatment of:
Explanation & Rationale
A. Syphilis is caused by the bacterium Treponema pallidum and is treated primarily with penicillin G. Isoniazid and rifampin are not effective against spirochetes and have no role in treating syphilis. B. Isoniazid and rifampin are first-line antitubercular medications used in the treatment of tuberculosis (TB). They work by inhibiting bacterial cell wall synthesis (isoniazid) and RNA synthesis (rifampin), effectively targeting Mycobacterium tuberculosis. These medications are often given in combination to prevent drug resistance and achieve a full cure. C. Cellulitis, a bacterial infection of the skin and subcutaneous tissues, is commonly caused by Streptococcus or Staphylococcus species. Standard treatment involves beta-lactam antibiotics, such as penicillin or cephalosporins. Isoniazid and rifampin are not effective for cellulitis. D. Trichinosis is a parasitic infection caused by Trichinella spiralis, typically contracted from undercooked pork. Treatment involves antiparasitic medications such as mebendazole or albendazole, not antitubercular drugs.