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    Miami Dade College Pharmacology NUR1141 Proctored Exam

    The physician has ordered combination therapy for the client with Helicobacter pylori. The nurse plans to do medication education. What will the best plan by the nurse include?

    Explanation & Rationale

    A. Combination therapy has the best outcomes when omeprazole, propranolol, bismuth salicylate are used. Propranolol is not an antibiotic and is not part of the standard combination therapy for H. pylori. Bismuth subsalicylate may be used in some regimens, but the standard involves a proton pump inhibitor, clarithromycin, and amoxicillin or metronidazole. B. Combination therapy has the best outcomes when omeprazole, clarithromycin, and amoxicillin are used. This is the correct choice. The standard combination therapy for H. pylori infection includes a proton pump inhibitor (such as omeprazole), clarithromycin, and amoxicillin or metronidazole. C. The use of sucralfate along with antibiotics is the best combination therapy for peptic ulcer disease. Sucralfate is not typically part of the standard antibiotic combination therapy for H. pylori. It is a cytoprotective agent that may be used to treat ulcers but is not a primary component in eradicating H. pylori. D. Various antibiotics are used to eradicate the bacteria that are responsible for the development of peptic ulcer disease. While this statement is true, it does not specify the standard combination therapy. The most common antibiotics used in combination therapy for H. pylori include clarithromycin and amoxicillin or metronidazole, along with a proton pump inhibitor.

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