The practical nurse (PN) is caring for a client who has a prescription for loratadine by mouth daily as needed. Which sign indicates to the PN that there is a need to administer the medication?

A. Red papules and pustules on the face: These lesions are typically associated with acne or bacterial skin infections rather than an allergic reaction. Loratadine, an antihistamine, would not be indicated for these types of skin eruptions. B. Ulceration on the corner of the upper lip: Lip ulcers are generally caused by trauma, infection, or nutritional deficiencies. Antihistamines like loratadine are not effective in treating ulcerative lesions and would not be the appropriate intervention. C. Red welts widespread over the chest: Widespread red welts are characteristic of urticaria, an allergic reaction involving histamine release. Loratadine, as an H1-receptor antihistamine, is indicated to reduce itching, redness, and swelling in this situation. D. Ecchymosis and petechiae on the legs: These findings suggest bleeding or platelet disorders rather than histamine-mediated allergic reactions. Loratadine would not address the underlying cause, so it is not appropriate to administer in this case.