To control asthma, a client in a residential treatment facility uses a fluticasone propionate and salmeterol discus inhalation system, which provides an inhaled powdered form of these combined medications. Which instruction should the nurse provide to this client's caregivers?

A. When using the discus, have the client breathe out rapidly into the mouthpiece: Clients should exhale away from the mouthpiece before inhaling the medication. Breathing out into the mouthpiece can blow away the powdered medication, making the dose ineffective.B. Offer the discus to the client for use during an acute asthma attack: Fluticasone and salmeterol are used for long-term control of asthma, not for immediate relief during an acute attack. A short-acting bronchodilator like albuterol is needed for acute symptom management.C. Explain that the client should not use the discus more than twice daily: The fluticasone/salmeterol combination is typically prescribed for use twice daily. Exceeding the recommended frequency increases the risk of side effects such as throat irritation, infections, and cardiovascular effects.D. Clients using the discus may experience decreased blood pressure: While beta-agonists can sometimes have cardiovascular effects, salmeterol is a long-acting beta-agonist primarily targeting the airways. Decreased blood pressure is not a common or expected side effect of fluticasone/salmeterol inhalers. Increased heart rate or palpitations are more potential cardiovascular effects, but significant hypotension is unlikely.