Two nurses are discussing the theories of drug-receptor interaction. Which statements are true regarding the affinity of a drug and for its receptor? (Select all that apply)
Explanation & Rationale
Choice A reason: Affinity is not about dosage form but the strength of drug-receptor binding. Dosage is unrelated to receptor interaction, so this is incorrect for affinity’s definition. Choice B reason: Low affinity means weak attraction to receptors, not strong. High affinity indicates strong binding, so this statement is incorrect. Choice C reason: High affinity means strong attraction between drug and receptor, enhancing binding and effect. This is accurate, making it a correct choice. Choice D reason: Affinity influences potency; higher affinity often means greater potency at lower doses. This relationship is correct, making it a correct choice. Choice E reason: Affinity is the strength of attraction between drug and receptor, a fundamental pharmacological concept. This definition is accurate, so this is a correct choice.