Untreated or improperly treated diabetes is the primary cause of the following: (Select All that Apply.)

A. Pancreatitis: Pancreatitis is not directly caused by diabetes. It has different etiologies, such as gallstones, alcohol use, and certain medications. B. New blindness: Diabetes is a leading cause of new cases of blindness among adults due to diabetic retinopathy, which damages the blood vessels in the retina. C. Nontraumatic lower extremity amputations: Diabetes is the primary cause of nontraumatic lower extremity amputations due to complications such as peripheral neuropathy and poor circulation leading to severe infections and gangrene. D. Hepatitis: Hepatitis is an inflammation of the liver, commonly caused by viral infections, alcohol abuse, or other factors, not directly by diabetes E. Renal failure: Diabetes is a major cause of end-stage renal disease (ESRD) due to diabetic nephropathy, which damages the kidneys over time.