What are the common side effect(s) associated with ondansetron? Select all that apply.
Explanation & Rationale
A. Pain: Ondansetron is not commonly associated with pain as an adverse effect. Pain may occur at the injection site if administered IV, but it is not a systemic or frequent side effect of the medication. B. Bradycardia: Ondansetron generally does not cause bradycardia. Cardiac effects are rare and more commonly involve QT interval prolongation rather than heart rate reduction. C. Vomiting: Vomiting is the symptom ondansetron is designed to prevent. Its occurrence after administration may indicate treatment failure or underlying illness rather than a side effect. D. Diarrhea: Diarrhea is a recognized gastrointestinal side effect of ondansetron, resulting from altered gut motility and serotonin receptor modulation in the intestines. E. Headache: Headache is a common systemic side effect, likely due to central serotonin receptor effects. It is frequently reported by clients receiving ondansetron and is usually mild to moderate in intensity.