What is a therapeutic use of methadone?

A. Methadone is not used to treat hypertension; it is an opioid agonist with no primary effect on blood pressure management. B. Fibromyalgia management typically involves medications such as duloxetine, pregabalin, or non-opioid analgesics; methadone is not a standard treatment. C. Methadone is used for opioid use disorder as a long-acting opioid agonist. It helps manage withdrawal symptoms, reduce cravings, and support long-term maintenance therapy, allowing clients to stabilize and reduce illicit opioid use. D. Methadone is not indicated for muscle spasm relief; muscle relaxants or non-opioid analgesics are preferred for that purpose.