NursingPlex
    Sign In
    Pharmacology proctored exam 6123 - Chicago state university

    What is the brand name of celecoxib?

    Explanation & Rationale

    A. MS Contin is the brand name for morphine sulfate extended-release, a potent opioid analgesic. It functions as a pure mu-opioid receptor agonist to modulate the perception of pain. It is not chemically related to the sulfonamide-derived compound celecoxib. B. Voltaren is the brand name for diclofenac, a non-selective nonsteroidal anti-inflammatory drug. It inhibits both cyclooxygenase-1 and cyclooxygenase-2 enzymes to reduce prostaglandin synthesis. Celecoxib is a distinct pharmaceutical agent with a different selectivity profile than diclofenac. C. Celebrex is the brand name for celecoxib, a selective cyclooxygenase-2 inhibitor. It primarily targets the inducible isoform of the cyclooxygenase enzyme to decrease inflammatory prostaglandin production. This specificity reduces the incidence of gastrointestinal toxicity compared to non-selective agents. D. Motrin is the brand name for ibuprofen, a propionic acid derivative and non-selective nonsteroidal anti-inflammatory drug. It provides analgesic and antipyretic effects by inhibiting both cyclooxygenase isoforms. It is not the proprietary name for the selective inhibitor celecoxib.

    🔒 Submit your answer to reveal