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    Pharmacology proctored exam 6123 - Chicago state university

    What is the brand name of clobetasol propionate (topical)?

    Explanation & Rationale

    A. Temovate is the proprietary brand name for clobetasol propionate, a super-high potency topical corticosteroid. It induces phospholipase A2 inhibitory proteins, known as lipocortins, which control the biosynthesis of potent inflammatory mediators. This reduces cutaneous inflammation and pruritus. B. Neomycin is an aminoglycoside antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit. It is not the brand name for clobetasol propionate. It is commonly used for topical prophylaxis against minor skin infections. C. Nystatin is a polyene antifungal agent used to treat cutaneous or mucocutaneous candidiasis. It binds to ergosterol in the fungal cell membrane, creating pores that lead to the leakage of intracellular components. It is not associated with clobetasol. D. Neosporin is a brand name for a triple antibiotic combination containing neomycin, polymyxin B, and bacitracin. It is used for the prevention of infection in minor wounds and lacks corticosteroid activity. It does not contain the ingredient clobetasol.

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