What is the generic name of Plaquenil?
Explanation & Rationale
A. Pantoprazole is the generic name for the brand Protonix, a proton pump inhibitor. It irreversibly binds to the hydrogen-potassium ATPase enzyme system at the secretory surface of gastric parietal cells. It is used to treat erosive esophagitis and hypersecretory conditions. B. Hydrocodone bitartrate with acetaminophen is the generic combination found in brands like Vicodin or Lortab. It combines an opioid agonist with a non-opioid analgesic to manage moderate to severe pain. It is not the active constituent in Plaquenil. C. Hydroxychloroquine sulfate is the generic name for Plaquenil, an aminoquinoline derivative. It interferes with digestive vacuole function within sensitive malarial parasites and inhibits rheumatoid factor and acute phase reactants. This medication is indicated for systemic lupus erythematosus and rheumatoid arthritis. D. Prednisolone acetate is a glucocorticoid often found in ophthalmic suspensions such as Pred Forte. It decreases inflammation by suppressing the migration of polymorphonuclear leukocytes and reversing increased capillary permeability. It is a steroid, not a disease-modifying antirheumatic aminoquinoline.