What would the nurse stress to a 17-year-old client who is capable of pregnancy and has been prescribed isotretinoin for treatment of severe cystic acne?

A. Drink at least 1000 mL of fluid daily: While maintaining adequate hydration is generally recommended for overall health, fluid intake does not prevent the serious risks associated with isotretinoin. Emphasizing hydration alone would not address the critical concern of teratogenicity in pregnancy. B. Use dependable birth control: Isotretinoin is highly teratogenic and can cause severe birth defects if pregnancy occurs during therapy. The nurse should stress that sexually active clients of childbearing potential must use reliable contraception, often requiring two methods, before starting isotretinoin, throughout treatment, and for a short period after discontinuation. C. Stay inside on sunny days: Isotretinoin can increase photosensitivity, but strict avoidance of sunlight is not the primary safety concern. Sun protection measures are advised, but the teratogenic risk remains the most critical issue for a client capable of pregnancy. D. Avoid alcoholic beverages: Alcohol can affect liver function, and isotretinoin can also be hepatotoxic. Although avoiding alcohol is advisable to reduce liver strain, this precaution is secondary to preventing pregnancy due to the drug’s severe teratogenic effects.