When caring for a 13-year-old with muscular dystrophy receiving corticosteroids to slow disease progression, which of the following medication side effects would you assess for?

Choice A rationaleWeight gain is a common side effect of corticosteroids due to fluid retention and increased fat deposition. Corticosteroids stimulate appetite and alter fat metabolism, leading to central obesity and moon face, which are classic findings.Choice B rationaleMood changes, including irritability, depression, or euphoria, are linked to corticosteroid therapy as these medications affect the central nervous system. Neuropsychiatric symptoms can vary widely and may impact the adolescent’s quality of life and social interactions.Choice C rationaleWeight loss is not a typical side effect of corticosteroids. These medications are more associated with increased appetite and fat redistribution, leading to weight gain rather than weight loss, making this an incorrect choice.Choice D rationaleChronic fatigue is not directly attributed to corticosteroids. While muscle weakness can occur due to protein catabolism, it is not synonymous with fatigue. Corticosteroids often cause insomnia, which could indirectly lead to tiredness, but this is not a primary effect.Choice E rationaleOsteoporosis is a long-term side effect of corticosteroids due to their impact on calcium metabolism and bone resorption. These medications decrease calcium absorption, increase calcium excretion, and suppress osteoblast activity, leading to reduced bone density.