When does the addictive/dependent personality, due to continuous drug use, result in an inability to function without the substance, and little or no contact with other people?

A. late stage In the late stage, individuals are often isolated, physically dependent, and unable to function without the drug. B. end stage Often used interchangeably with late stage, but "late stage" is the more appropriate clinical term. C. middle stage Characterized by increasing use and noticeable life disruption, but functioning may still be present. D. early stage In the early stage, individuals may deny the problem and often maintain normal routines despite increasing use.