When educating a patient about taking iron tablets, which of the following instructions should the nurse provide?

A. Milk contains calcium, which binds to iron and reduces its absorption, so iron tablets should not be taken with milk. B. Crushing the tablet may be appropriate for some formulations, but mixing with yogurt or other dairy can interfere with absorption; the nurse should instruct clients to follow manufacturer instructions. C. Taking iron with water does not prevent constipation; iron commonly causes constipation regardless of fluid intake, although adequate hydration can help manage it. D. Antacids and calcium supplements can bind to iron and significantly reduce its absorption, so clients should be instructed to take iron at least 2 hours apart from these substances to ensure effectiveness.