When educating a patient with tuberculosis (TB) about medication adherence, which of the following instructions is most important?

Rationale: A. Doubling the next dose after missing one is unsafe and increases the risk of toxicity. B. TB treatment must continue for the entire prescribed duration (often 6–12 months); stopping early can lead to relapse and drug resistance. C. Taking medications at the same time every day is the most important instruction because it maintains consistent therapeutic drug levels, ensures effectiveness, and reduces the risk of resistance. D. Skipping doses, even on weekends, decreases treatment effectiveness and increases the risk of multidrug-resistant TB.