Which actions by the nurse demonstrate an understanding of pharmacokinetics and the nurse's role in medication therapy? (Select All that Apply.)

A. Verify the dose based on the client's age, weight, and organ function: Pharmacokinetics involves absorption, distribution, metabolism, and excretion. Age, body weight, and hepatic or renal function directly affect drug metabolism and elimination. Verifying appropriate dosing helps prevent toxicity or subtherapeutic effects. B. Administering the medication at the prescribed time to maintain therapeutic drug levels: Maintaining consistent serum drug levels supports steady state and therapeutic effectiveness. Proper timing reflects understanding of half-life and dosing intervals. C. Ignoring drug interactions if the client reports no side effects: This is incorrect. Drug interactions can alter metabolism or excretion and may not immediately produce noticeable side effects. Nurses must always assess for potential interactions. D. Recommending herbal supplements to enhance medication effectiveness: This is inappropriate. Herbal supplements can significantly alter drug absorption or metabolism and should not be recommended without provider oversight. E. Educating the client about how food or other medications can affect absorption: Food and concurrent medications can alter absorption rates and bioavailability. Client education supports safe and effective medication therapy. F. Monitoring the client's liver and kidney function before administering medications: The liver and kidneys are primary organs for drug metabolism and excretion. Monitoring their function helps guide safe dosing and prevent accumulation or toxicity.