Which assessment by the nurse would be a sign of neurotoxicity related to chemotherapy?

Rationale: A. Euphoria is not a common sign of chemotherapy-induced neurotoxicity. It may occur with certain medications affecting mood, but it is not indicative of nerve damage from chemotherapy. B. Paresthesia, which includes numbness, tingling, or a “pins and needles” sensation, is a hallmark sign of peripheral neuropathy, a common form of neurotoxicity caused by chemotherapy. Drugs such as cisplatin, paclitaxel, and vincristine can damage peripheral nerves, leading to sensory changes, motor weakness, or altered coordination. Early recognition allows interventions to prevent further nerve damage and improve quality of life. C. Nausea is a common gastrointestinal side effect of chemotherapy, but it is not a sign of neurotoxicity. While it may indirectly affect the nervous system through dehydration or electrolyte imbalance, it does not indicate direct nerve injury. D. Hallucinations are not typical of chemotherapy-related neurotoxicity. They may occur with high-dose corticosteroids, CNS involvement by cancer, or certain medications, but they are not a standard indicator of peripheral neuropathy.