Which B vitamin deficiency is associated with cheilosis, glossitis, vascularization of the cornea, and itchy dermatitis of the scrotum and vulva?

A. Pyridoxine (vitamin B6): Deficiency in vitamin B6 can cause peripheral neuropathy, irritability, depression, and seizures. While glossitis may occur, the combination of cheilosis and corneal vascularization is not typical of B6 deficiency. B. Riboflavin (vitamin B2): Riboflavin deficiency is classically associated with cheilosis, glossitis, corneal vascularization, and seborrheic dermatitis affecting areas like the scrotum and vulva. These findings are hallmark signs of ariboflavinosis. C. Thiamine (vitamin B1): Thiamine deficiency causes beriberi and Wernicke-Korsakoff syndrome, with manifestations including neuropathy, heart failure, and confusion. It is not linked to cheilosis or corneal changes. D. Niacin (nicotinic acid): Niacin deficiency results in pellagra, characterized by the “three Ds”: dermatitis, diarrhea, and dementia. The dermatitis is photosensitive but does not involve cheilosis or corneal vascularization.