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    Pharmacology proctored exam - Pain seizure

    Which client should the nurse expect to receive a lower-than-usual dose of benzodiazepines?

    Explanation & Rationale

    A. A client whose anxiety is due to pain caused by gallstones: While this client is experiencing discomfort, their liver function is not necessarily impaired. Benzodiazepines may be used cautiously, but there is no need to automatically reduce the dose. B. A client with alcoholic liver disease: Benzodiazepines are metabolized by the liver. In clients with alcoholic liver disease, impaired hepatic function can lead to drug accumulation and toxicity. Therefore, a lower dose is necessary to prevent excessive sedation or respiratory depression. C. A client who has irritable bowel syndrome: IBS affects the gastrointestinal tract but does not significantly alter the metabolism of benzodiazepines. These clients typically require standard dosing unless other factors such as age or comorbidities are present. D. A client who is 6 months postgastrectomy: Gastrectomy may alter drug absorption but not metabolism, which primarily occurs in the liver. Adjustments in dosing are not required unless absorption is severely compromised or other organ systems are affected.

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