Which combination of medication classes would be most appropriate to manage a client's manifestations of sinusitis characterized by nasal congestion and headache due to inflammation?

A. Antihistamines and expectorants: Antihistamines are primarily used for allergic rhinitis and may excessively dry out the sinuses, potentially worsening a headache. Expectorants help thin bronchial secretions but are not the primary treatment for sinus-related nasal congestion. This combination does not directly address the inflammatory pain of a sinus headache. B. Antibiotics and antivirals: These agents target specific pathogens and do not provide immediate relief for the mechanical symptoms of congestion or pain. Antibiotics are only appropriate if a bacterial etiology is confirmed, and antivirals are rarely used for standard sinusitis. They lack the analgesic properties required to manage an acute headache. C. Antitussives and mucolytics: Antitussives are used to suppress a non-productive cough and have no role in relieving sinus pressure or headaches. Mucolytics thin mucus but do not provide the vasoconstriction needed to reduce nasal passage edema. This combination fails to address the vascular and inflammatory components of the patient's manifestations. D. Decongestants and analgesics: Decongestants like pseudoephedrine cause vasoconstriction of the nasal mucosa to reduce edema and improve drainage. Analgesics such as ibuprofen or acetaminophen target the inflammatory pathways responsible for the headache and localized facial pain. Together, they provide the most comprehensive symptomatic relief for sinusitis.