Which finding for a patient admitted with glomerulonephritis indicates to the nurse that treatment has been effective?

A. The antistreptolysin-O (ASO) titer has decreased: A high ASO titer indicates a recent streptococcal infection, which can precede glomerulonephritis. However, a decrease in this lab value does not directly reflect improvement in kidney function or resolution of the condition itself. B. The urine dipstick is negative for nitrites: Nitrites in urine suggest a bacterial infection such as a urinary tract infection. Glomerulonephritis is immune-mediated, not infectious, so the absence of nitrites is not a marker of treatment effectiveness in this case. C. The patient denies pain or burning with voiding: Painful urination is associated with lower urinary tract infections or bladder inflammation. Glomerulonephritis usually presents with proteinuria, hematuria, and edema, so resolution of dysuria is not a reliable measure of treatment success. D. The periorbital and peripheral edema are resolved: Reduction in edema indicates improved kidney function, fluid balance, and response to therapy. Since fluid retention is a hallmark of glomerulonephritis, resolution of swelling is the clearest sign that treatment has been effective.