Which finding indicates a client may be experiencing carbidopa-levodopa toxicity?
Explanation & Rationale
A. Mild tremors in hands: Tremors are a hallmark symptom of Parkinson’s disease and are expected in clients prior to or during therapy. Mild hand tremors alone do not indicate drug toxicity. B. Tongue protrusion: Involuntary movements, including tongue protrusion, facial grimacing, or choreiform movements, are signs of dyskinesia associated with carbidopa-levodopa toxicity. These hyperkinetic movements reflect excessive dopaminergic stimulation. C. Mild nausea after each meal: Nausea is a common early side effect of carbidopa-levodopa and usually diminishes over time or with administration adjustments. It does not indicate toxicity unless severe or persistent. D. Significant weight gain: Weight gain is not a recognized adverse effect or marker of toxicity with carbidopa-levodopa therapy. It may occur due to lifestyle factors but is unrelated to drug overuse.