Which lab finding would the nurse expect to be elevated in a patient with alcoholic hepatitis?
Explanation & Rationale
Choice A reason: Hemoglobin levels are typically normal or decreased in alcoholic hepatitis, not elevated. Chronic alcohol consumption often leads to nutritional deficiencies, such as folate or B12 deficiency, and toxic effects on the bone marrow, resulting in macrocytic anemia or other forms of decreased red blood cell production. Choice B reason: While creatinine may rise if the patient develops hepatorenal syndrome, it is not a primary diagnostic marker for alcoholic hepatitis itself. Creatinine reflects renal function, whereas the primary pathology in this scenario is acute hepatocellular inflammation and necrosis directly caused by prolonged and heavy ethanol ingestion. Choice C reason: Albumin levels are typically decreased, not elevated, in patients with chronic liver disease and alcoholic hepatitis. The liver's biosynthetic capacity is impaired, leading to hypoalbuminemia. This reduction in oncotic pressure contributes to the development of ascites and peripheral edema often seen in these clinical cases. Choice D reason: AST is characteristically elevated in alcoholic hepatitis, often showing a specific ratio where the AST is at least twice the level of alanine aminotransferase (ALT). This occur because alcohol has a direct toxic effect on the hepatocytes and specifically depletes mitochondrial enzymes, making AST a sensitive marker.