Which medication is contraindicated in patients with a history of angioedema or patients with swelling on their lips?

A. Losartan: Losartan is an angiotensin II receptor blocker (ARB). While ARBs can rarely cause angioedema, the risk is much lower compared to ACE inhibitors. They are often prescribed as alternatives when patients cannot tolerate ACE inhibitors due to angioedema. B. Atenolol: Atenolol is a beta-blocker used for hypertension and cardiac conditions. It is not associated with angioedema and does not carry a contraindication for patients with this history. C. Clopidogrel: Clopidogrel is an antiplatelet agent that prevents clot formation. It is not linked to angioedema and does not pose a contraindication for clients with prior swelling of the lips. D. Lisinopril: Lisinopril is an ACE inhibitor, and this class of drugs is strongly associated with angioedema due to increased bradykinin levels. A history of angioedema or lip swelling is a clear contraindication to its use.