Which nursing assessment is the priority for a client receiving cholestyramine?

A. Assessment of 24-hour urine: Cholestyramine does not primarily affect renal function or require monitoring of urinary output. It acts locally in the gastrointestinal tract to bind bile acids and is not absorbed systemically, making urine assessment a lower priority. B. Auscultation of heart sounds: While important in a comprehensive assessment, heart sounds are not directly affected by cholestyramine therapy. Unless the client has a known cardiac condition, this is not the most relevant or immediate nursing assessment. C. Auscultation of bowel sounds in all four quadrants: Cholestyramine commonly causes gastrointestinal side effects such as constipation, bloating, and potential bowel obstruction. Monitoring bowel sounds helps detect early signs of impaired motility or obstruction. D. Palpation for peripheral edema in the lower extremities: Peripheral edema is not a common adverse effect of cholestyramine. While it could be relevant in clients with underlying heart or kidney issues, it is not a direct concern linked to this medication.