Which of the following are other uses of Clonidine besides blood pressure management?(Select All that Apply.)

A. Clonidine does not treat hyperthyroidism; it acts on the central nervous system to reduce sympathetic outflow, not thyroid hormone activity. B. Clonidine is sometimes used off-label to help manage symptoms of depression or anxiety, particularly when related to hyperarousal or withdrawal. C. Clonidine is used to reduce withdrawal symptoms and cravings in opioid dependence, helping manage agitation, anxiety, and sweating during detoxification. D. Clonidine has no antimicrobial properties and is not used for infection management. E. Clonidine does not raise blood sugar levels; if anything, it may cause mild decreases in glucose due to reduced sympathetic tone. F. Clonidine is not indicated for diabetes management; it primarily affects blood pressure and withdrawal symptoms, not glucose control.