Which of the following client education points about ibuprofen and acetaminophen should the nurse include? Select all that apply.

Rationale: A. Ibuprofen should not be redosed this quickly. The typical dosing interval is every 6–8 hours, depending on the formulation. Taking an additional dose too soon increases the risk of gastrointestinal, renal, and cardiovascular adverse effects. B. Combining NSAIDs (e.g., ibuprofen with naproxen or aspirin) increases the risk of GI bleeding, kidney injury, and other adverse effects. NSAIDs should not be combined unless specifically directed by a healthcare provider. C. Ibuprofen is an NSAID, which can irritate the stomach lining and increase the risk of gastritis or ulcers. Taking it with food, milk, or antacids helps reduce GI irritation. D. Acetaminophen is not an NSAID and does not affect platelet function or the GI mucosa. It is generally safer for patients at risk of GI bleeding or those who require normal coagulation. E. Incorrect for typical adult dosing. The maximum recommended daily dose for healthy adults is 3,000–4,000 mg, depending on guidelines and liver function. 1,200 mg is usually a limit for over-the-counter preparations or special populations, but education should reflect safe adult dosing and emphasize not exceeding the recommended maximum. F. NSAIDs like ibuprofen can cause GI bleeding, so patients should be instructed to report symptoms such as dark/tarry stools, vomiting blood, or abdominal pain.